200 Billion Panax Ginseng Exosomes for Scalp & Hair
P198 ExoNature HB Plus is a professional-grade Korean scalp booster delivering 200 billion lyophilised Panax Ginseng exosomes per vial, an industry-leading concentration and a 5x increase over the standard ExoNature HB variant. Isolated from 15-year Panax Ginseng callus cultures and supported by Leontopodium Alpinum (Edelweiss) callus culture extract for antioxidant defence, these plant-derived extracellular vesicles act as cellular messengers, carrying bioactive compounds into the dermal papilla and follicular environment to help support hair regeneration, scalp barrier health, and a healthier anagen growth phase.
The freeze-dried exosome powder is reconstituted at the point of treatment using either the P198 Boosting Solution (sold separately) or sterile non-pyrogenic saline, preserving the integrity of the exosome cargo and the supporting peptide complex until the moment of application. Alongside the ginseng-derived exosomes, the formula contains Tripeptide-1, Copper Tripeptide-1, Oligopeptide-29, Palmitoyl Pentapeptide-4, and Edelweiss callus culture extract: a multi-pathway approach to thinning hair, weakened follicles, and compromised scalp condition.
Why P198 ExoNature™ HB Plus?
200 Billion Panax Ginseng Exosomes
ExoNature HB Plus delivers 200 billion lyophilised Panax Ginseng exosomes per vial, isolated from 15-year ginseng callus cultures. One of the highest plant exosome concentrations available in professional scalp therapy, and a 5× increase over the standard ExoNature HB variant. Supported by Edelweiss callus culture extract for antioxidant and soothing defence.
Plant-Derived Exosome Source
ExoNature HB Plus uses exclusively plant-derived exosomes isolated from Panax Ginseng callus cultures. Plant-source exosomes offer a distinct profile of bioactive cargo, supporting cell-to-cell signalling associated with follicular renewal. An option suited to practitioners and patients who prefer a botanical exosome treatment.
Multi-Peptide Hair & Scalp Complex
Beyond the exosomes, the formula combines Tripeptide-1, Copper Tripeptide-1, Oligopeptide-29, and Palmitoyl Pentapeptide-4: four of the most clinically studied peptides in trichology. Together they help support follicle activity, the anagen growth phase, dermal papilla cell proliferation, and the scalp’s structural matrix.
Lyophilised for Maximum Potency
The exosome complex and peptides are freeze-dried to preserve the delicate vesicle structures and bioactive cargo until the moment of use. At treatment, the powder is reconstituted with the P198 Boosting Solution (sold separately) or sterile non-pyrogenic saline, ensuring every active reaches the scalp at peak potency with no degradation from premature aqueous storage.
HB vs HB Plus
Both variants share the identical formulation, peptide complex, and treatment protocol. The Plus variant simply delivers 5× the exosome load.
P198 ExoNature HB
P198 ExoNature HB Plus
Benefits
Treatment Schedule
Recommended Course
One vial per session, reconstituted on the day of treatment with the P198 Boosting Solution (sold separately) or sterile non-pyrogenic saline. Sessions spaced every 3 weeks. Delivered via 0.5mm microneedling (MTS), dermastamp, or RF-microneedling for direct dermal penetration into the scalp’s follicular layer.
Visible Results
Improvements in scalp condition and shedding may be noticed within the first few weeks. New hair growth and increased density typically develop progressively across the full course as follicles transition into the anagen phase.
Maintenance
After completing the initial course, periodic maintenance sessions can help sustain follicular activity, scalp health, and the cumulative effects of the exosome and peptide complex.
Product Specification
Full Ingredients: Water, Panax Ginseng Vesicles, Leontopodium Alpinum Callus Culture Extract, Dipeptide-2, Tripeptide-1, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Oligopeptide-1, Oligopeptide-29.
Frequently Asked Questions
P198 ExoNature™ HB Plus is a professional Korean scalp and hair booster built around 200 billion lyophilised Panax Ginseng exosomes per vial, an industry-leading concentration isolated from 15-year ginseng callus cultures, supported by Edelweiss callus culture extract for antioxidant and soothing effect. The freeze-dried powder is reconstituted at the point of treatment using either the P198 Boosting Solution (sold separately) or sterile non-pyrogenic saline, and applied to the scalp via 0.5mm microneedling. It is designed to help support hair regeneration and follicular health for those experiencing thinning, weakened, or compromised hair.
The Plus variant delivers 200 billion exosomes per treatment, compared to 40 billion in the standard ExoNature HB, a 5× higher exosome load. Both variants share the identical INCI and treatment protocol; the Plus differentiator in the ExoNature line is exosome concentration alone. Both are supplied as single lyophilised vials and reconstituted at the point of treatment using the P198 Boosting Solution (sold separately) or sterile non-pyrogenic saline.
Both ExoNature HB Plus and Filcore HB Plus are professional-grade exosome scalp boosters from the P198 range, but they use different exosome sources. ExoNature HB Plus uses plant-derived exosomes from Panax Ginseng callus cultures; Filcore HB Plus uses human umbilical cord blood-derived exosomes. Each source has its own bioactive profile and is well-suited to different practitioner preferences and patient needs. They are also packaged differently: ExoNature ships as a powder vial only and is reconstituted at the point of treatment, while Filcore is supplied with a bundled activator solution.
The formula contains four trichology-focused peptides: Tripeptide-1, Copper Tripeptide-1, Oligopeptide-29, and Palmitoyl Pentapeptide-4. Tripeptide-1 and its copper-bound form, Copper Tripeptide-1, are among the most clinically studied follicle-supporting peptides, helping to support dermal papilla cell activity and the anagen growth phase. Oligopeptide-29 helps support follicular activity, while Palmitoyl Pentapeptide-4 contributes to the scalp’s collagen matrix. Edelweiss callus culture extract, Dipeptide-2, and Oligopeptide-1 add antioxidant, soothing, and keratinocyte support.
ExoNature HB Plus is supplied as a lyophilised exosome powder vial. To prepare for treatment, reconstitute the powder using either the P198 Boosting Solution (sold separately) or sterile non-pyrogenic saline. Once reconstituted, the solution is then applied topically to the scalp as part of a MTS treatment, a dermastamp treatment, or an RF-microneedling device treatment. Each vial is for a single treatment session only and must be used immediately after reconstitution.
A standard course is 5 sessions spaced every 3 weeks. Improvements in scalp condition and shedding may be noticed within the first few weeks. New hair growth and increased density typically develop progressively across the full course and may continue to improve in the weeks after the final session. Maintenance sessions every 3–6 months can help sustain results.
ExoNature HB Plus is designed for adults experiencing hair thinning, reduced hair density, weakened hair quality, or scalp irritation. It is also well suited as a post-procedure recovery treatment after hair transplant surgery and as a complement to other hair-loss protocols. As a plant-derived exosome product, it offers an alternative to human-derived options for practitioners and patients who prefer a botanical formulation. Always perform a professional scalp assessment before treatment.
Store the lyophilised powder vials at 2–8°C, away from direct sunlight. Once opened or reconstituted, the solution should be used immediately within the same treatment session and not stored for later use, as the exosomes and peptide complex begin to degrade once in aqueous solution.
P198 ExoNature™ HB Plus is manufactured by Primoris International Co., Ltd., South Korea.
