P198 ExoNature SB Plus (skin)

ExoNature SB Plus is the high-strength skin member of the P198 ExoNature line: 200 billion lyophilised Panax Ginseng exosomes in a 2ml vial, alongside Edelweiss callus culture extract and six signal peptides. It is for skin that has become dry, dull, rough, slack or uneven, and it works by helping to support the skin’s own renewal rather than sitting on the surface.

Exosome count. Plus is the concentrated version of the ExoNature skin booster, carrying 200 billion Panax Ginseng exosomes per vial against 40 billion in the standard ExoNature SB, the same five-fold step as the HB and HB Plus scalp pair. Same 2ml vial, same lyophilised format, five times the exosome load.

Exosomes are nano-sized vesicles that cells use to pass signals and cargo to one another. ExoNature’s come from Panax Ginseng, Korea’s most prized root, and carry its ginsenosides (Rb1, Rg1, Rc and Compound Y) and polyphenols inside a lipid membrane the skin readily takes up. PSC1994-EXPG™ is the manufacturer’s name for that ingredient, produced on its PSC1994® plant stem cell exosome platform using high-pressure dispersion rather than crushing and centrifuging, which gives smaller, more uniform vesicles built for absorption.

SB is the skin booster, HB is the hair and scalp booster. Both carry 200 billion Panax Ginseng exosomes with Edelweiss and a six-peptide complex, but the peptides are tuned to the job: SB Plus includes Oligopeptide-32, a signal peptide associated with the dermal-epidermal junction that keeps skin firm, where HB Plus uses Oligopeptide-29 for the follicle. Buy SB Plus for the face and body, HB Plus for the scalp.

Two exosome families from the same Korean lab, built on different sources. ExoNature uses plant-derived Panax Ginseng exosomes; Filcore uses ExoHealer™ exosomes from a different origin. Each has its own bioactive profile and its own following among practitioners and clients. ExoNature is the choice for anyone who wants a botanical exosome.

Six. Tripeptide-1 and Copper Tripeptide-1 for collagen and elastin signalling and repair, Palmitoyl Pentapeptide-4 for the dermal matrix, Oligopeptide-32 for the dermal-epidermal junction, Oligopeptide-1 for keratinocyte renewal and Dipeptide-2 for microcirculation and decongestion. The manufacturer groups them under the name USC1994-SPC-CBP.

Yes. ExoNature SB Plus is supplied as a lyophilised (freeze-dried) powder in a sealed 2ml vial, which is what keeps 200 billion exosomes stable and potent until the moment of treatment. It is reconstituted with the P198 Boosting Solution (sold separately) or sterile non-pyrogenic saline, and used immediately once mixed.

The P198 Boosting Solution is the manufacturer’s own reconstitution partner, formulated to give the exosomes something to work with: PDRN, hyaluronic acid, glutathione, 20 amino acids, 10 vitamins and 12 minerals in a 3ml vial. Saline reconstitutes the powder; the Boosting Solution turns the treatment into a full nutrient complex.

Each box carries the manufacturer’s authenticity sticker, which can be scanned to confirm the product is genuine.

Nothing. EvoCyte is a company (one we are not associated with), not a product. The product is P198 ExoNature SB Plus, manufactured in Korea by Primoris International.

One vial per treatment. The published protocols using SB Plus ran three sessions spaced two to three weeks apart. Your practitioner will tailor the course to the skin in front of them.

Primoris International Co., Ltd. of Seoul, the company behind the P198 ExoHealer and ExoNature brands. Its roots go back to 1994, the year its stem cell research began, which is where every ingredient platform gets the “1994” in its name and the brochure gets its 30 years of stem cell skin science. ExoNature launched in March 2025.