Plant-Derived Exosome Technology for Skin & Scalp
BotanicExo® is a 100% vegan Korean exosome treatment that harnesses the regenerative power of plant stem cell extracellular vesicles (EVs). At its core is LEXosome™ — a patented exosome derived from Lithospermum erythrorhizon (Gromwell root), a botanical with over 2,000 years of documented use in traditional East Asian medicine for wound healing, anti-inflammation, and skin repair.
Using SpheBio’s proprietary 3D Tissue Culture Platform, BotanicExo achieves 90× higher exosome concentration than conventional extraction methods, with 4× more uniform quality for superior absorption. The dual-vial system — freeze-dried exosome powder mixed fresh with a nutrient-rich active solution — delivers a potent combination of plant EVs, amino acids, B-vitamins, niacinamide, glutathione, and NAD+ for comprehensive skin and scalp revitalisation.
Why BotanicExo?
Patented LEXosome™ Plant Exosomes
BotanicExo uses LEXosome™ — a patented plant-derived exosome extracted from Lithospermum erythrorhizon stem cells using SpheBio’s 3D Tissue Culture Platform. This advanced production method delivers 90× higher exosome concentration and 4× more uniform particle quality compared to conventional extraction, ensuring superior cell-signalling potency and absorption.
100% Vegan & Cruelty-Free
Every ingredient in BotanicExo is plant-derived or synthetic. Certified vegan by the Korea Agency of Vegan Certification and Services, it contains no animal-derived components, making it a cruelty-free alternative to human or animal-sourced exosome products. Suitable for practitioners and clients seeking ethical, plant-based aesthetic treatments.
Dual-Purpose: Skin & Scalp
BotanicExo is formulated for both skin rejuvenation and scalp revitalisation. The same EV-rich formula that drives collagen synthesis and cellular repair in the skin also supports hair follicle cell growth and scalp health. One product, two treatment pathways — making it a versatile addition to any aesthetic practice.
Freshly Mixed Dual-Vial System
The freeze-dried exosome powder and nutrient-rich active solution are mixed immediately before each treatment, ensuring maximum potency and bioactivity. This dual-vial format preserves the integrity of the delicate EVs, peptides, and growth-signalling molecules until the moment of application.
Benefits
Treatment Schedule
Recommended Course
One set (powder + active solution) per session, applied to the skin or scalp via microneedling or similar techniques. Sessions are spaced every 2 weeks, with cumulative improvement building across the full course.
Visible Results
Initial improvements in skin tone, hydration, and texture are often visible within the first week. Progressive results in collagen density, firmness, and pigmentation reduction develop over subsequent sessions.
Maintenance
After completing the initial course, periodic maintenance sessions help sustain the regenerative, brightening, and collagen-boosting effects. Frequency can be adjusted based on individual skin or scalp condition.
Product Specification
Exosome source: 100% plant-derived from Lithospermum erythrorhizon (Gromwell root) stem cell culture. Contains no animal-derived ingredients. Produced using SpheBio’s patented 3D Tissue Culture Platform for 90× higher exosome concentration and 4× more uniform quality vs conventional extraction.
Frequently Asked Questions
BotanicExo® is a vegan Korean exosome skin and scalp treatment. It uses LEXosome™ — a patented plant-derived exosome extracted from Lithospermum erythrorhizon (Gromwell root) stem cells — combined with niacinamide, glutathione, amino acids, B-vitamins, NAD+, and hyaluronic acid. The dual-vial system (freeze-dried powder + active solution) is mixed fresh before each session for maximum potency.
Exosomes are microscopic extracellular vesicles that act as cell-to-cell messengers. BotanicExo’s plant exosomes are derived from Lithospermum erythrorhizon stem cells and carry a rich payload of miRNAs, peptides, and cytokines. When applied to the skin or scalp, they deliver regenerative signals directly to cells, promoting tissue repair, collagen synthesis, and cellular renewal at a fundamental level.
Yes. BotanicExo is 100% plant-derived and contains no animal-sourced ingredients. It is certified vegan by the Korea Agency of Vegan Certification and Services, and is also CPNP/SCPN registered. This makes it a cruelty-free alternative to human or animal-sourced exosome products.
Yes. BotanicExo is specifically formulated as a “Skin and Scalp Revitalizing Kit”. The same EV-rich formula that drives skin regeneration and collagen production also supports hair follicle health and scalp revitalisation. For scalp treatments, it is applied to clean, dry scalp and can be combined with microneedling or LED therapy.
Add the 5ml active solution to the vial of freeze-dried exosome powder using a syringe. Gently shake for approximately 20 seconds until fully dissolved. The mixed solution is then ready for application. Use immediately after mixing, and do not reuse — each set is for a single treatment session only.
A recommended course is 3 to 5 sessions spaced every 2 weeks. Initial improvements in skin tone and hydration are often visible within the first week. Progressive results in collagen density, firmness, and pigmentation reduction develop across the full course. Maintenance sessions every 2 to 3 months can help sustain results.
Lithospermum erythrorhizon, commonly known as Gromwell or “Zicao” in traditional Chinese medicine, is a perennial plant from the Boraginaceae family. Its roots have been used for over 2,000 years across East Asia for wound healing, anti-inflammatory, and antioxidant applications. The key bioactive compound, shikonin, has been extensively studied for its anti-ageing, anti-pigmentation, and tissue repair properties. BotanicExo extracts its patented LEXosome™ exosomes from this plant’s stem cell cultures.
BotanicExo stands apart in several ways. Its exosomes are 100% plant-derived (not human or animal-sourced), making it vegan and cruelty-free. SpheBio’s patented 3D Tissue Culture Platform produces exosomes at 90× higher concentration with 4× more uniform quality compared to conventional methods. It also works for both skin and scalp in a single formulation, and the active solution includes a comprehensive blend of niacinamide, glutathione, amino acids, B-vitamins, and NAD+ rather than just HA alone.
Store away from direct sunlight. The freeze-dried powder format keeps the exosomes stable without refrigeration. Once mixed with the active solution, use immediately. Do not store or reuse the mixed solution.
